Bicalutamide and Third-Generation Aromatase Inhibitors in Testotoxicosis
نویسندگان
چکیده
منابع مشابه
Third-generation Aromatase Inhibitor Improved Adult Height in a Japanese Boy with Testotoxicosis
In this study, we report a Japanese boy with testotoxicosis due to a heterozygous mutation [p. A572V] in the LH/CGR gene, who was the first boy treated with a third-generation aromatase inhibitor (AI) and reached his adult height in Japan. He showed accelerated growth and rapid penile growth from 3 yr of age and was diagnosed as having testotoxicosis. Combined treatment with anastrozole and spi...
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Use of aromatase inhibitors (AIs), exemestane, letrozole and anastrozole, for breast cancer therapy is associated with severe pain symptoms, the underlying mechanism of which is unknown. The electrophilic nature of AIs suggests that they may target the transient receptor potential ankyrin 1 (TRPA1) channel, a major pathway in pain transmission and neurogenic inflammation. AIs evoke TRPA1-mediat...
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متن کاملself-revision and third party revision in translation
اهمیت این پژوهش در آن بود که به گفت? بسیاری از پژوهشگرانِ حوز? بازبینی ترجمه، ادبیات موجود در این زمینه به لحاظ نظری و عملی چندان قوی نیست و بخش های موجود نیز برداشت مناسبی از این مرحل? فرایند ترجمه ندارند، اگرچه اخیراً توجه به آن به صورت نظام مند افزایش یافته است. در عین حال، پژوهش های موجود از یک سو بر دگربازبینی بیشتر از خودبازبینی تأکید دارند و از دیگر سو تنها به لحاظ نظری به این موضوع می پرد...
15 صفحه اولLetter to the Editor regarding “Testotoxicosis: Report of Two Cases, One with a Novel Mutation in Luteinizing Hormone/Choriogonadotropin Receptor Gene”
©Jo ur nal of Cli ni cal Re se arch in Pe di at ric En doc ri no logy, Pub lis hed by Ga le nos Pub lis hing. I read with great interest a paper recently published in JCRPE (2015) by Özcabı et al (1) entitled " Testotoxicosis: Report of Two Cases, One with a Novel Mutation in LHCGR Gene ". The authors report two cases with testotoxicosis caused by activating mutations in luteinizing hormone/cho...
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ژورنال
عنوان ژورنال: PEDIATRICS
سال: 2010
ISSN: 0031-4005,1098-4275
DOI: 10.1542/peds.2010-0596